Both enclomiphene and clomiphene are drugs belonging to the selective estrogen receptor modulator (SERM) class. It is widely used for fertility treatment and ovulation induction in women.
The main difference between enclomiphene and clomiphene is their molecular structure. Enclomiphene is the trans isomer of clomiphene and its chemical structure is the mirror image of clomiphene. As a result, it has a different effect on the body compared to clomiphene.
Enclomiphene is thought to work by indirectly increasing testosterone levels in the body. It does this by blocking the action of estrogen in the hypothalamus and pituitary gland, which are responsible for regulating the production of hormones such as testosterone. As a result, the body increases the production of luteinizing hormone (LH), which stimulates testosterone production in the testicles.
The typical half-life of enclomiphene is about 5 days. The recommended dose of enclomiphene depends on individual factors such as age, medical history, and specific reasons for treatment.
It is most commonly used at 12.5mg per day for men, this can be increased but may not yield compaaratively greater results. Like all drugs, enclomiphene can cause side effects. Common side effects include hot flashes, headaches, and mood swings. Less common side effects include vision changes, fatigue, and abdominal pain.
