Yohimbine is a natural alkaloid found in the bark of the Paucinistaria yohimbe tree. It acts as an alpha-2 adrenergic receptor antagonist in the body. That is, it blocks the effects of certain neurotransmitters that bind to these receptors.This increases the release of norepinephrine and epinephrine, which can increase heart rate, blood pressure, and fat mobilization. Yohimbine has a typical half-life of about 2 hours.
Yohimbine is also often used in the sencondary treatment of erectile disfunction as a more natural alternative is known drugs like Viagra.
Yohimbine is commonly used as a dietary supplement for weight loss and improving athletic performance. The recommended dose of yohimbine is 5-20 mg, depending on the individual and desired effect. However, it is important to note that yohimbine can cause serious side effects such as high blood pressure, heart palpitations, and anxiety.