BP Tirzepatide 60 Pen (60mg Tirzepatide), this medication is the first dual GIP/GLP-1 receptor co-agonist approved for the treatment of type 2 diabetes
Tirzepatide (LY3298176) is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist, recently developed and finally approved in May 2022 by the Food and Drug Administration for the treatment of T2DM as an adjunct to diet and exercise. In subjects with T2DM, dual GIP and GLP-1 receptor agonism with tirzepatide, compared to single GLP-1 receptor agonism with semaglutide, produced significantly more significant improvements in total insulin secretion rate and insulin sensitivity, reflecting a significant improvement compared to semaglutide.
Similar effects were also documented in another mechanistic trial comparing tirzepatide with dulaglutide, another GLP-1 receptor agonist, suggesting that dual receptor agonism might indeed be responsible for improving insulin sensitivity, especially since the observed effect was shown to be only partially attributable to weight loss. Furthermore, the effect of tirzepatide on delayed gastric emptying is comparable to that induced by single GLP-1 receptor agonism.
Benefits of Tirzepatide:
- Blood Sugar Control: Tirzepatide mimics GLP-1 and GLI, regulating blood sugar levels. It prompts insulin release when blood sugar is high and reduces glucagon production, which raises blood sugar.
- Weight Management: Tirzepatide promotes weight loss by increasing satiety, reducing food intake, and aiding in weight reduction.
- Cardiovascular Benefits: Some studies suggest Tirzepatide may reduce the risk of heart-related complications in type 2 diabetes.
Dosage Instructions: Dosages of BP Tirzepatide 30 Pen vary based on the product and its use (diabetes or obesity).
Tirzepatide is a subcutaneous injection.
General guidelines are as follows:
- For diabetes management, start with 2.5 mg once a week. Depending on the response and tolerance, increase to 5 mg or 7.5 mg once a week upwards of a maximum 15 mg per week.
- For obesity treatment, the recommended dose is 5 mg once a week, administered on the same day weekly, at a time of your choosing.
Always adhere to your healthcare provider’s dosage instructions, tailored to your specific condition and response.
Side Effects: While not universal, Tirzepatide may have side effects:
- Gastrointestinal Issues: Nausea, vomiting, diarrhea, and abdominal pain, especially when starting, may improve over time.
- Hypoglycemia: Tirzepatide has a lower risk of causing low blood sugar compared to some diabetes drugs, but it can still occur, particularly when used with other blood sugar-lowering medications.
- Injection Site Reactions: Some individuals may experience redness, itching, or pain at the injection site.
- Pancreatitis: Pancreas inflammation has been reported as a potential side effect although it is a rare side effect.
- Kidney Function: Tirzepatide may affect kidney function, requiring monitoring in some cases.
Discuss potential side effects and concerns with your healthcare provider when considering Tirzepatide treatment.
Half-life: BP Tirzepatide boasts a relatively lengthy half-life of about one week, allowing for once-weekly dosing. This extended action duration contributes to its efficacy in managing blood sugar and promoting weight loss.
In summary, Tirzepatide effectively manages type 2 diabetes and aids in weight loss. It provides multiple advantages, including blood sugar control and weight management. However, like all medications, it may cause side effects, and proper dosing guidance should be followed under healthcare provider supervision.
